Endocrine Abstracts

Thyroid nodules are common in the population. Ultrasound would detect nodules, in about 25% of the adult and half of the elderly population(>60 years). Only 5% of these nodules are malignant, and 60–70% of the detected benign nodules, remains similar or decrease in size during the long term follow-up. Few nodules, i.e >1.3 cm, would function autonomously and cause thyrotoxicosis. Rarely, large single nodules or multinodulated glands could cause compressive symptom...

Riedel thyroiditis (RT) is a rare kind of chronic thyroiditis which may be a part of a multifocal systemic fibrosis syndrome. When it is generally accepted as a thyroid manifestation of IgG4 related systemic disease. We hereby present a 54 year old woman who was suffering from shortness of breath because of a mass lesion originating from thyroid and invading neck and upper mediastinal structures, leading to dyspnea and dysphagia, as shown by CT, 15 years ago. After an isthmect...

Due to inhibition affect on proliferation, motility, resistance to apoptosis and growth of metastasis, the epidermal growth factor receptor (EGFR) inhibitor erlotinib and vascular endothelial growth factor receptor (VEGF) and EGFR inhibitor vandetanib are viable treatment options for treatment of advanced non-small cell lung cancer and thyroid cancer respectively. Advanced non-small cell lung carcinomas (NSCLC) or medullary and differentiated thyroid carcinomas (MTC and DTC) m...

Objective: Thyroid hemiagenesis is a rare form of thyroid dysgenesis, in which one thyroid lobe fails to develop. The true prevalence of this rare abnormality is about 0.05–0.2% in normal population. We aimed to determine prevalence of thyroid hemiagenesis in patients with various thyroid disorders and a normal population in a mild to moderate iodine-deficient area.Subjects and methods: The clinical and thyroid ultrasonography records of 4.833 patie...

Riedel thyroiditis (RT) is a rarest form of thyroiditis, and characterized by dense fibrosis of the throid gland and infiltration into surrounding tissues. RT generally presents with local symptoms association with compression and also fibrotic process can impact thyroid and parathyroid functions. We report a case with RT which presents with compression findings and also hypoparathyroidism and hypothyroidism. 30 year old women visited our outpatient clinic with a complaint of ...

Introduction: Minimally invasive surgery is an alternative surgical approach for primary hyperparathyroidism with less surgical trauma and anesthesia complications. Neck ultrasonography and scintigraphy are still the first step tools for localisating parathyroid lesions. Intact parathyroid hormone (PH) determination in washout samples is really very useful when parathyroid lesions can not be easily distinguished from thyroid lesions or sometimes lymph nodes.<p class="abste...

Objectives: We aimed to find if there is any relationship between vitamin D levels and clinical, laboratory parameters and osteoporosis, in primary hyperparathyroidism (PHPT).Material and methods: 128 patients with PHPT and 30 patients as a control group were analysed. Patients with PHPT were grouped due to vitamin D levels and levels low than 20 μg/ml accepted as deficiency.Results: Patients with 25-OH vitamin D <20 &#956...

Objectives: Coexisting thyroid nodules affect the treatment choice for PHPT. We aimed to evaluate the incidence of concomitant thyroid nodules in patients with primary hyperparathyroidism and to investigate the relationship between thyroid nodule volume, thyroid gland volume and thyroid nodules with clinical and laboratory parameters.Materials and methods: This study was carried out at Ankara University Endocrinology and Metabolism Department. 183 patien...

Background: Recombinant human thyroid-stimulating hormone (rhTSH)-stimulated serum thyroglobulin (Tg) (s-Tg) and (131)I whole-body scanning (WBS) are supposed to provide equal diagnostic information with thyroxine withdrawal (THW) at follow-up thyroid cancer patients without the symptoms of hypothyroidism. We aimed to compare the WBS and s-Tg levels after thyrogen injection and thyroid hormone withdrawal for tumor recurrence/persistance according to the risk groups.<p clas...

Surveys for the assessment of the iodine status, carried out between 1997 and 1999 in Turkey showed that the country was severe to moderately iodine deficient. (National median UIC 36 μg/l, goiter prevalence % 31.8). Therefore, a national IDD control program had been implemented and mandatory salt iodization were applied by July 1999 with 50–70 mg/kg KI or 25–40 mg/kg KIO3 to the household salt.Objectives: To evaluate the curren...